Lonoke’s Original Pharmacy

Trust your health and wellness to the drug store that’s been providing professional pharmacy services since the 1940s!


GetĀ Free Delivery

Whether you’re homebound, staying inside for health and safety, or looking for convenience and ease of service, Lyons Drug Store is here for you! Call in your prescription or refill your prescriptions online and schedule a FREE delivery to manage your health from the comfort of your own home! Quick and courteous delivery at no cost – that’s hometown service!

Click below to schedule your delivery or contact us to see how we can help you manage your health and wellness!

Pharmacy Services

Everything you need in one place

Our pharmacy stocks over-the-counter and prescription drugs to meet every need! Convenience and care are our promise to you – our professional pharmacists and courteous clerks will help you find the right solution to get you feeling better and back to a full life.

Whether you need to make a quick stop for essentials or to consult a pharmacist about your prescription medication, Lyons Drug Store is here for you!

Medication Services

We’re your hometown health and wellness team – offering quick, convenient, and caring service from professional pharmacists.

  • Prescription Refills and Transfers

  • Home Delivery
  • Mail Delivery
  • Medication Adherence
  • Medication Therapy Management
  • Immunizations
  • Medication Synchronization
  • Private Consultation

Over The Counter

Seasonal allergies and headaches and nasal congestion – oh my! We stock quick remedies for household ailments big and small.

  • Pain Medication

  • Cold and Allergy Medication
  • Vitamins and Supplements
  • First Aid Items
  • FlavorRx
  • Pill Glide
  • Competitive Pricing


Affordable treatments for men with ED

As men age, a decrease in testosterone is normal – but you don’t have to suffer from ED or the high cost of little blue pills. We stock treatments for ED at affordable prices. Come in for a consultation or order for delivery – Lyons Drug Store ships to any address in Arkansas quickly and discreetly!

Learn more about sildenafil – the active ingredient in drugs like Cialis and Viagra – by clicking below, or contact us for more information!