Serving Lonoke for over 80 years

Lyons Drug Store

We’ve been serving Lonoke since the 1940s. Experience friendly, professional pharmacy service with a hometown attitude and atmosphere!

Call Lyons Drug Store
Three men in suits stand outside a vintage storefront labeled Lyons Drugs Rexall Store and Soda Fountain. The window displays various products and signs, including Malt Bar and Ice Cream Service. The scene has an early 20th-century appearance.
A brick storefront at night with illuminated signs that read Gifts and Lyons Drug Store. The store windows display a variety of items. Several lights illuminate the buildings facade.
An older man with glasses, wearing a suit, holds a certificate in front of a backdrop with the Arkansas Pharmacists Association logo.
A person with short dark hair and glasses is smiling, wearing a white lab coat. Another person with long blonde hair is partially visible, also in a lab coat. They are indoors, possibly in a professional setting.

Refill Online

Convenience, care, and comfort combine when you refill your prescriptions online from the comfort and safety of your own home! Order refills in our app and pick them up at the store or schedule free delivery and we’ll bring wellness to you.

Download Refill App
A person wearing glasses and a black collared shirt stands in front of shelves filled with bottles. The background displays various containers, possibly medications, in a pharmacy setting.

As seen on TV

You may have seen your hometown pharmacist on TV! We advertise the great service and convenient care of Lyons Drug Store and Gift Shop across the state.

Learn about Sildenafil
A group of people in purple football jerseys is gathered outdoors. Some are sitting on a hay bale, and one child is sitting on a womans lap. They are smiling, and there are trees in the background.

Community Involvement

We’re invested in Central Arkansas

For over 80 years, Lonoke and central Arkansas have been our home! We are proud to give back to the community that has given us so much. Wellness is a team effort – and we’re thrilled to be on your team!

About Lyons Drug Store
A person with short dark hair and glasses is smiling, wearing a white lab coat. Another person with long blonde hair is partially visible, also in a lab coat. They are indoors, possibly in a professional setting.
★ ★ ★ ★ ★

“Wonderful friendly people and I trust them with all my family’s medication.”

– Pat B.

A smiling man with a bald head and white beard, wearing dark-framed glasses and a gray polo shirt, stands in front of a blurred background of buildings.
★ ★ ★ ★ ★

“Great small town customer focused pharmacy that goes out of their way to help you. They have a pretty awesome gift shop also!”

– Michael F.

A person in a green and white outfit stands on a wood floor beside a festive wall decoration featuring three stacked snowmen with red scarves, set against a backdrop with snowflakes. A separate snowman figure is attached to the wall.
★ ★ ★ ★ ★

“any type or kind gift you need Lyons has it.so nice and pretty. my favorite store to shop for gifts.”

– Joyce P.

A holiday-themed table display features red candles, a bowl filled with pinecones, cinnamon sticks, and red berries, and a wrapped gift with a red ribbon, set on a beige tablecloth.

Our Gift Shop

Something for everyone

Whether you’re celebrating the holidays or a special day for someone in your life, we have cards, gifts, and local products to show how much you care!

Learn More