Serving Lonoke for over 80 years

Lyons Drug Store

We’ve been serving Lonoke since the 1940s. Experience friendly, professional pharmacy service with a hometown attitude and atmosphere!

Refill Online

Convenience, care, and comfort combine when you refill your prescriptions online from the comfort and safety of your own home! Order refills in our app and pick them up at the store or schedule free delivery and we’ll bring wellness to you.

As seen on TV

You may have seen your hometown pharmacist on TV! We advertise the great service and convenient care of Lyons Drug Store and Gift Shop across the state – and into Illinois and Missouri.

Community Involvement

We’re invested in Central Arkansas

For over 80 years, Lonoke and central Arkansas have been our home! We are proud to give back to the community that has given us so much. Wellness is a team effort – and we’re thrilled to be on your team!

★ ★ ★ ★ ★

“Wonderful friendly people and I trust them with all my family’s medication.”

– Pat B.

★ ★ ★ ★ ★

“Great small town customer focused pharmacy that goes out of their way to help you. They have a pretty awesome gift shop also!”

– Michael F.

★ ★ ★ ★ ★

“any type or kind gift you need Lyons has nice and pretty. my favorite store to shop for gifts.”

– Joyce P.

Our Gift Shop

Something for everyone

Whether you’re celebrating the holidays or a special day for someone in your life, we have cards, gifts, and local products to show how much you care!